In the intricate machinery of life, protein kinases stand out as master regulators, wielding their power to orchestrate a symphony of cellular processes. These molecular maestros exert their control through a subtle yet profound mechanism known as phosphorylation, selectively attaching phosphate groups to target proteins. This transformative modification alters the protein's structure and function, dictating its fate within the cell.
The Chemistry of Phosphorylation
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Proteins are the workhorses of life, performing a vast array of essential functions, from catalyzing biochemical reactions to building and maintaining cellular structures. Protein engineering, a rapidly evolving field at the intersection of biology, chemistry, and computer science, aims to harness the power of these molecular machines by designing and manipulating their structure and function to address a wide range of challenges in medicine, biotechnology, and beyond.
Traditionally, pro...
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